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A University Estd. Under Odisha Legislature Act of 2017

Sanjib Mohanty

Tel : +91-889550-1174
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Dr. Sanjib Mohanty is a Senior Physician from the city of Rourkela, Odisha, India. He was the Ex-Director of Ispat General Hospital (IGH) in Rourkela, who has been heavily involved in both clinical and scientific research - focused on understanding the pathophysiology of cerebral malaria in Indian patients over the past 30 years. He has participated in landmark drug trials and reserach papers on the subject of malaria in top journals like Lancet, JID, CID, Malaria etc. Currently He is the Mentor cum Research Consultant of the US NIH- funded International Centers for Excellence in Malaria Research (ICEMR) in collaboration with New York University School of Medicine, USA at IGH Rorukela, known as the CSCMi (Center for the Study of Complex Malaria in India) which aims to better understand the pathology of cerebral malaria using revolutionary MRI techniques. Besides, he is also the Senior consultant for the UK DFID sponosred multi-centered project on Tracking Artemisisnin Resistance in Malaria (TRAC II) at IGH Rourkela in collaboration with Oxford University UK and Mahidol University Bangkok, Thailand. Besides being an Internal Medicine & Expert ICU Physician involved in clinical and scientific research for the past 30 years, his major activities also included:

1. Antimalarial drug trials e.g. SEQUAMAT (Artesunate vs Quinine) Trial in severe malaria (Lancet 2005)
2. Unravelling the pathogenesis of cerebral malaria by neuroimaging (CT) including the largest series of cerebral malaria in adults published in CID 2011, and more recently MRI, as published in Malaria Journal in 2014)
3. WHO faculty for “Management of severe Malaria” (Training doctors from India & Nepal).
4. Expert Member of the National Drug Policy on Malaria, Govt. Of India.
5. Research Publications, reviews and book chapters in Malaria: around 70 with more than 1600 citations

Publications

1. Mohanty, A. K., Sahu, P. K., and Mohanty, S. (2016) Hyperparasitaemia and phagocytosis of Plasmodium falciparum in fatal cerebral malaria. Journal of Vector Borne Diseases 53, 290

2. Rao, P. N., Uplekar, S., Kayal, S., Mallick, P. K., Bandyopadhyay, N., Kale, S., Singh, O. P., Mohanty, A., Mohanty, S., and Wassmer, S. C. (2016) A method for amplicon deep sequencing of drug resistance genes in Plasmodium falciparum clinical isolates from India. Journal of clinical microbiology 54, 1500-1511 

3. Mohanty, A. K., Sahu, P. K., Pattnaik, R., Mohanty, A., Mahanta, K. C., and Mohanty, S. (2016) Fatal Cerebral Malaria with Multi-Organ Dysfunction and Oleander Poisoning. Malaria Control & Elimination 5, 1-3

4. Toure, O. A., Valecha, N., Tshefu, A. K., Thompson, R., Krudsood, S., Gaye, O., Rao, B. H. K., Sagara, I., Bose, T. K., and Mohanty, S. (2016) A Phase 3, Double-Blind, Randomized Study of Arterolane Maleate–Piperaquine Phosphate vs Artemether–Lumefantrine for Falciparum Malaria in Adolescent and Adult Patients in Asia and Africa. Clinical Infectious Diseases, ciw029

5. Fernandez-Arias, C., Rivera-Correa, J., Gallego-Delgado, J., Rudlaff, R., Fernandez, C., Roussel, C., Götz, A., Gonzalez, S., Mohanty, A., and Mohanty, S. (2016) Anti-Self Phosphatidylserine Antibodies Recognize Uninfected Erythrocytes Promoting Malarial Anemia. Cell host & microbe 19, 194-203

6. Satpathi, P., Satpathi, S., Mohanty, S., Mishra, S. K., Behera, P. K., and Maity, A. B. (2016) Helicobacter pylori infection in dyspeptic patients in an industrial belt of India. Tropical doctor, 0049475515626033

7. Kanchan, K., Pati, S., Mohanty, S., Mishra, S., Sharma, S., Awasthi, S., Venkatesh, V., Habib, S., and Consortium, I. G. V. (2015) Polymorphisms in host genes encoding NOSII, C-reactive protein, and adhesion molecules thrombospondin and E-selectin are risk factors for Plasmodium falciparum malaria in India. European Journal of Clinical Microbiology & Infectious Diseases 34, 2029-2039

8. Hanson, J., Lee, S. J., Hossain, M. A., Anstey, N. M., Charunwatthana, P., Maude, R. J., Kingston, H. W., Mishra, S. K., Mohanty, S., and Plewes, K. (2015) Microvascular obstruction and endothelial activation are independently associated with the clinical manifestations of severe falciparum malaria in adults: an observational study. BMC medicine 13, 1

9. Herdman, M. T., Sriboonvorakul, N., Leopold, S. J., Douthwaite, S., Mohanty, S., Hassan, M. M. U., Maude, R. J., Kingston, H. W., Plewes, K., and Charunwatthana, P. (2015) The role of previously unmeasured organic acids in the pathogenesis of severe malaria. Critical Care 19, 1

10. Kanchan, K., Jha, P., Pati, S. S., Mohanty, S., Mishra, S. K., Sharma, S. K., Awasthi, S., Venkatesh, V., and Habib, S. (2015) Interferon-γ (IFNG) microsatellite repeat and single nucleotide polymorphism haplotypes of IFN-α receptor (IFNAR1) associated with enhanced malaria susceptibility in Indian populations. Infection, Genetics and Evolution 29, 6-14

11. Wassmer, S. C., Taylor, T. E., Rathod, P. K., Mishra, S. K., Mohanty, S., Arevalo-Herrera, M., Duraisingh, M. T., and Smith, J. D. (2015) Investigating the pathogenesis of severe malaria: a multidisciplinary and cross-geographical approach. The American journal of tropical medicine and hygiene 93, 42-56

12. Imwong, M., Woodrow, C. J., Hendriksen, I. C., Veenemans, J., Verhoef, H., Faiz, M. A., Mohanty, S., Mishra, S., Mtove, G., and Gesase, S. (2015) Plasma concentration of parasite DNA as a measure of disease severity in falciparum malaria. Journal of Infectious Diseases 211, 1128-1133

13. Hanson, J., Phu, N. H., Hasan, M. U., Charunwatthana, P., Plewes, K., Maude, R. J., Prapansilp, P., Kingston, H. W., Mishra, S. K., and Mohanty, S. (2015) The clinical implications of thrombocytopenia in adults with severe falciparum malaria: a retrospective analysis. BMC medicine 13, 1

14. Sahu, P. K., Satpathi, S., Behera, P. K., Mishra, S. K., Mohanty, S., and Wassmer, S. C. (2015) Pathogenesis of cerebral malaria: new diagnostic tools, biomarkers, and therapeutic approaches. Frontiers in cellular and infection microbiology 5 

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